User profiles for Lake Douglas

Douglas F. Lake

Arizona State University
Verified email at asu.edu
Cited by 2835

Sample entropy analysis of neonatal heart rate variability

DE Lake, JS Richman, MP Griffin… - American Journal of …, 2002 - journals.physiology.org
Abnormal heart rate characteristics of reduced variability and transient decelerations are
present early in the course of neonatal sepsis. To investigate the dynamics, we calculated …

Cardiovascular oscillations at the bedside: early diagnosis of neonatal sepsis using heart rate characteristics monitoring

…, BP Kovatchev, JS Richman, DE Lake - Physiological …, 2011 - iopscience.iop.org
We have applied principles of statistical signal processing and nonlinear dynamics to
analyze heart rate time series from premature newborn infants in order to assist in the early …

Sample entropy

JS Richman, DE Lake, JR Moorman - Methods in enzymology, 2004 - Elsevier
Publisher Summary This chapter presents Sample Entropy (SampEn) alogorithm as an
alternative method for entropy estimation in real world data. The chapter discusses the problems …

Mortality reduction by heart rate characteristic monitoring in very low birth weight neonates: a randomized trial

…, JA Perez, C Palmer, GJ Stukenborg, DE Lake… - The Journal of …, 2011 - Elsevier
OBJECTIVE: To test the hypothesis that heart rate characteristics (HRC) monitoring improves
neonatal outcomes. STUDY DESIGN: We conducted a two-group, parallel, individually …

Accurate estimation of entropy in very short physiological time series: the problem of atrial fibrillation detection in implanted ventricular devices

DE Lake, JR Moorman - American Journal of Physiology …, 2011 - journals.physiology.org
Entropy estimation is useful but difficult in short time series. For example, automated detection
of atrial fibrillation (AF) in very short heart beat interval time series would be useful in …

The emerging role of QSOX1 in cancer

DF Lake, DO Faigel - Antioxidants & redox signaling, 2014 - liebertpub.com
Significance: Quiescin sulfhydryl oxidase 1 (QSOX1) is an enzyme that oxidizes thiols during
protein folding, reducing molecular oxygen to hydrogen peroxide. Tumor cells may take …

[HTML][HTML] Abnormal heart rate characteristics preceding neonatal sepsis and sepsis-like illness

…, TM O'Shea, EA Bissonette, FE Harrell, DE Lake… - Pediatric …, 2003 - nature.com
Late-onset neonatal sepsis is a significant cause of morbidity and mortality, and early
detection could prove beneficial. Previously, we found that abnormal heart rate characteristics (…

Heart rate characteristics: novel physiomarkers to predict neonatal infection and death

MP Griffin, DE Lake, EA Bissonette, FE Harrell Jr… - …, 2005 - publications.aap.org
Objective. Monitoring of regulated physiologic processes using physiomarkers such as heart
rate variability may be important in the early diagnosis of subacute, potentially catastrophic …

[HTML][HTML] Heart rate characteristics and clinical signs in neonatal sepsis

MP Griffin, DE Lake, TM O'Shea, JR Moorman - Pediatric research, 2007 - nature.com
To test the hypothesis that heart rate characteristic (HRC) monitoring adds information to
clinical signs of illness in diagnosing neonatal sepsis, we prospectively recorded clinical data …

[HTML][HTML] New-onset atrial fibrillation in the critically ill

…, C Ruminski, JP DiMarco, DE Lake… - Critical care …, 2017 - journals.lww.com
Objective: To determine the association of new-onset atrial fibrillation with outcomes,
including ICU length of stay and survival. Design: Retrospective cohort of ICU admissions. We …